For fun, I asked Chat GPT about my medical case, and pretty much gave the vague answers..

Interesting because Dr. Dutta once suggested he thought I might have a Lupus variant (hence why I joined Lupus LA a long time ago),

not entirely convinced that’s what I have, whenever the immune system is miswired autoimmune/immune all blurr together in one hot sticky mess —

Which is why immunoglobulin is so good, because it helps cover both 😍

What I asked:

Suggestions for a human immunodeficiency where the patient gets infections and does not create an elevated white cell blood count or a generate a fever

Chat GPT response:

ChatGPT

If a patient exhibits symptoms of immunodeficiency where they experience frequent infections but do not show elevated white blood cell counts or generate a fever, it is important to consult a medical professional for a proper diagnosis and appropriate treatment. However, here are a few potential suggestions or considerations for further discussion with a healthcare provider:

1. Primary Immunodeficiency Disorders: There are various genetic disorders that can lead to a weakened immune system. These disorders affect the development and function of immune cells. Conditions such as severe combined immunodeficiency (SCID), common variable immunodeficiency (CVID) [our diagnosis!] or specific antibody deficiencies could be explored.
2. HIV/AIDS: While HIV infection often leads to decreased immune function and an increased susceptibility to infections, it may not always result in a high white blood cell count or fever. HIV attacks and destroys CD4+ T cells, which play a crucial role in the immune response. Consultation with a healthcare professional and appropriate testing can determine if HIV infection is a potential cause.
3. Autoimmune Disorders: Some autoimmune conditions can cause immunodeficiency by interfering with the normal functioning of the immune system. Examples include systemic lupus erythematosus (SLE), rheumatoid arthritis, or certain types of vasculitis. [Interesting because I had an unusual Spect scan years ago and was diagnosed with vasculitis, and I’ve had positive ANA] These conditions may lead to an increased risk of infections without necessarily causing elevated white blood cell counts or fevers.
4. Medications or Treatments: [Not this one since we’ve had it since birth.] Certain medications, such as corticosteroids or immunosuppressants used in autoimmune disorders, can suppress the immune system and increase susceptibility to infections. Chemotherapy or radiation therapy for cancer treatment may also weaken the immune system and result in a similar presentation.
5. Chronic infections: [I wonder if I got diverticulitis Jan 2023 in part because I had Covid Dec 2022, and Covid might weaken immune system] Chronic infections, such as tuberculosis or certain fungal infections, can lead to a compromised immune system over time, making the individual more susceptible to other infections. These conditions may not always cause an elevated white blood cell count or fever.

Remember, these suggestions are meant to provide a starting point for discussions with healthcare professionals. Only a qualified medical practitioner can conduct the necessary tests and evaluations to determine the exact cause of the symptoms and recommend appropriate treatment.